Sunday, 29 June 2008

Dispatched Homolog 2 is targeted by miR-214 through a combination of three weak microRNA recognition sites.

Overexpression of dre-miR-214 during development creates a curved-embryo phenotype which can also be created by disp2 knockdown. It was shown that miR-214 targets disp2 via 3 regions that show only loose pairing, in the same way that it targets Sufu.

[lab][connotea]

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