28SEP11

Hepatocellular Carcinoma resulting from chronic Hepatitis B may result from the actions of viral-human RNA hybrids. A hybrid of the human LINE protein and viral X protein was shown to sequester miR-122 while causin abnormal hepatic cell division in mice by promoting the epithelial-mesenchymal transition [2015]

Specific miRNA detection, using methylene blue as an indicator [2015]

Reduction of miR-761 is involved in exercise-induced muscle mitochondrial biogenesis in a mechanism that involves peroxisome-proliferator activated receptor -gamma coactivator 1 (PGC-1a). Overexpression of miR-761 downregulated the p38 MAPK signalling pathway [2015]

miR-21, -155, 19a, 17-5p, and let-7 were profiled in samples of normal and malignant breast tissue. Low let-7 was linked to lymphatic invasion, downregulation of miR-21 reflected necrosis. Both are suggested as markers for breast cancer prognosis [2015]

Profile of miRNA in exercising versus sedentary rats recovering from heart failure. Many more miRNAs were disregulated in the exercise group with miR-598, -429, -224, -425, and -221 particularly increased providing a potential role in cardioprotection. [2015].

Comparism of normalisation strategies in miRNA quantification using a reference small RNA [2015]